protein kinase r-like endoplasmic reticulum kinase

Cat No.	Product Name	Synonyms	Targets
T2614	GSK2606414		Apoptosis , PERK , Autophagy
	GSK2606414 is an oral-available and specific PERK inhibitor (IC50=0.4 nM).		Apoptosis , PERK , Autophagy
T2654	GSK2656157		Apoptosis , PERK , Autophagy
	GSK2656157 is a highly specific and ATP-competitive PERK inhibitor (IC50: 0.9 nM) in a cell-free assay. The selectivty is 500-fold higher against a panel of 300 kinases.		Apoptosis , PERK , Autophagy
T21976	ONO-8130		Prostaglandin Receptor
	ONO-8130 is an orally available antagonist of EP1 receptor.		Prostaglandin Receptor
T22436	Takeda-6d		VEGFR
	Takeda-6d, a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor, inhibits B-RAF and VEGFR2 with IC50 of 7.0nM and 2.2nM.		VEGFR
T6183	ISRIB (trans-isomer)	ISRIB,ISRIB trans-isomer,trans-isomer,trans-ISRIB	Apoptosis , PERK , Autophagy
	ISRIB (trans-isomer) (ISRIB trans-isomer), the trans-isomer of ISRIB, is a effective and specific PERK inhibitor (IC50: 5 nM).		Apoptosis , PERK , Autophagy
T63008	PERK-IN-5
	PERK-IN-5 is a highly selective, potent, orally active inhibitor of the protein kinase R-like endoplasmic reticulum (ER) kinase (PERK) that acts on PERK (IC50: 2 nM) and p-eIF2α (IC50: 9 nM). PERK-IN-5 significantly inhi...